Phenotypes associated with this allele

• Allele Symbol: Pt
• Allele Name: pintail
• Allele ID: MGI:1861192
• Summary: 5 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Pt/Pt	involves: CBA/Gr * PBR	MGI:3804633
hm2	Pt/Pt	involves: PBR	MGI:3804545
ht3	Pt/Pt^+	involves: CBA/Gr * PBR	MGI:3804631
ht4	Pt/Pt^+	involves: PBR	MGI:3804543
cx5	Pt/Pt sno/sno	involves: K/Gw	MGI:4359784

Genotype
MGI:3804633

hm1

• Allelic Composition: Pt/Pt
• Genetic Background: involves: CBA/Gr * PBR

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

embryo

abnormal notochord morphology ( J:14974 )

• noticeable at E10 as a reduced rate of cell division in the notochord

small notochord ( J:14974 )

limbs/digits/tail

abnormal caudal vertebrae morphology ( J:14974 )

• caused by a notochord defect

decreased caudal vertebrae number ( J:14974 )

• there are always fewer than ten caudal vertebrae

skeleton

abnormal caudal vertebrae morphology ( J:14974 )

• caused by a notochord defect

decreased caudal vertebrae number ( J:14974 )

• there are always fewer than ten caudal vertebrae

small intervertebral disk ( J:14974 )

• smaller intervertebral discs are the result of a small notochord

Genotype
MGI:3804545

hm2

• Allelic Composition: Pt/Pt
• Genetic Background: involves: PBR

mortality/aging

decreased survivor rate ( J:15 )

• survivors are healthy and fertile

preweaning lethality, incomplete penetrance ( J:15 )

• there is a high preweaning mortality

growth/size/body

decreased body size ( J:15 )

limbs/digits/tail

short tail ( J:15 )

• tails are much shorter than those of heterozygotes

abnormal tail tip morphology ( J:15 )

• tail tip is thin and threadlike

kinked tail ( J:15 )

• kinks are at the end of the tail

skeleton

abnormal nucleus pulposus morphology ( J:15 )

• there is a progressive reduction, from head to tail, of the nucleus pulposus

• reduction is more severe than found in heterozygous mice

small intervertebral disk ( J:15 )

Genotype
MGI:3804631

ht3

• Allelic Composition: Pt/Pt⁺
• Genetic Background: involves: CBA/Gr * PBR

limbs/digits/tail

decreased caudal vertebrae number ( J:14974 )

• the number of tail vertebrae is usually reduced by a third

skeleton

decreased caudal vertebrae number ( J:14974 )

• the number of tail vertebrae is usually reduced by a third

small intervertebral disk ( J:14974 )

• a smaller than normal notochord results in smaller than normal intervertebral disks in affected areas of the tail

embryo

abnormal notochord morphology ( J:14974 )

• at E10 there is a reduced rate of cell division in the notochord

small notochord ( J:14974 )

Genotype
MGI:3804543

ht4

• Allelic Composition: Pt/Pt⁺
• Genetic Background: involves: PBR

limbs/digits/tail

short tail ( J:15 )

• tail length is variable but longer than tails of homozygotes

abnormal tail tip morphology ( J:15 )

• tip of the tail is threadlike

kinked tail ( J:15 )

• kinks are near the end of the tail

skeleton

abnormal nucleus pulposus morphology ( J:15 )

• there is a progressive reduction, head to tail, of the nucleus pulposus

• the reduction is less severe in heterozygotes than in homozygotes

small intervertebral disk ( J:15 )

Genotype
MGI:4359784

cx5

• Allelic Composition: Pt/Pt; sno/sno
• Genetic Background: involves: K/Gw

mortality/aging

postnatal lethality ( J:5675 )

• mice die before weaning age