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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Hoxdtm3Ddu
targeted mutation 3, Denis Duboule
MGI:1857854
Summary 5 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Hoxdtm3Ddu/Hoxdtm3Ddu involves: 129S2/SvPas * C57BL/6 * SJL MGI:2178144
cx2
Hoxa11tm1Ssp/Hoxa11+
Hoxdtm3Ddu/Hoxd+
involves: 129S2/SvPas * C57BL/6 * CF-1 * SJL MGI:2178137
cx3
Hoxa11tm1Ssp/Hoxa11+
Hoxdtm3Ddu/Hoxdtm3Ddu
involves: 129S2/SvPas * C57BL/6 * CF-1 * SJL MGI:2178138
cx4
Hoxa11tm1Ssp/Hoxa11tm1Ssp
Hoxdtm3Ddu/Hoxdtm3Ddu
involves: 129S2/SvPas * C57BL/6 * CF-1 * SJL MGI:2178140
cx5
Del(2Hoxd11-Hoxd13)29Ddu/Hoxdtm3Ddu involves: 129S2/SvPas * C57BL/6 * SJL MGI:2178141


Genotype
MGI:2178144
hm1
Allelic
Composition
Hoxdtm3Ddu/Hoxdtm3Ddu
Genetic
Background
involves: 129S2/SvPas * C57BL/6 * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
phenotype observed in females
phenotype observed in males
N normal phenotype
normal phenotype
• no obvious phenotype, no defect detected in reproductive or skeletal systems




Genotype
MGI:2178137
cx2
Allelic
Composition
Hoxa11tm1Ssp/Hoxa11+
Hoxdtm3Ddu/Hoxd+
Genetic
Background
involves: 129S2/SvPas * C57BL/6 * CF-1 * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Hoxa11tm1Ssp mutation (0 available); any Hoxa11 mutation (3 available)
Hoxdtm3Ddu mutation (0 available); any Hoxd mutation (0 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
skeleton
N
• normal morphology of the ulna, radius, tibia, and fibula




Genotype
MGI:2178138
cx3
Allelic
Composition
Hoxa11tm1Ssp/Hoxa11+
Hoxdtm3Ddu/Hoxdtm3Ddu
Genetic
Background
involves: 129S2/SvPas * C57BL/6 * CF-1 * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Hoxa11tm1Ssp mutation (0 available); any Hoxa11 mutation (3 available)
Hoxdtm3Ddu mutation (0 available); any Hoxd mutation (0 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
limbs/digits/tail
• lack of distal fusion of tibia and fibula
• lack of distal fusion of tibia and fibula

skeleton
• lack of distal fusion of tibia and fibula
• lack of distal fusion of tibia and fibula




Genotype
MGI:2178140
cx4
Allelic
Composition
Hoxa11tm1Ssp/Hoxa11tm1Ssp
Hoxdtm3Ddu/Hoxdtm3Ddu
Genetic
Background
involves: 129S2/SvPas * C57BL/6 * CF-1 * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Hoxa11tm1Ssp mutation (0 available); any Hoxa11 mutation (3 available)
Hoxdtm3Ddu mutation (0 available); any Hoxd mutation (0 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
limbs/digits/tail
• thickening of radius
• thickening of ulna
• lack of distal fusion of tibia and fibula
• thickening of fibula
• lack of distal fusion of tibia and fibula
• thickening of tibia

skeleton
• thickening of radius
• thickening of ulna
• lack of distal fusion of tibia and fibula
• thickening of fibula
• lack of distal fusion of tibia and fibula
• thickening of tibia




Genotype
MGI:2178141
cx5
Allelic
Composition
Del(2Hoxd11-Hoxd13)29Ddu/Hoxdtm3Ddu
Genetic
Background
involves: 129S2/SvPas * C57BL/6 * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Del(2Hoxd11-Hoxd13)29Ddu mutation (2 available); any Del(2Hoxd11-Hoxd13)29Ddu mutation (2 available)
Hoxdtm3Ddu mutation (0 available); any Hoxd mutation (0 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
limbs/digits/tail
• reductions in size of digits II and V





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last database update
06/22/2016
MGI 6.04
The Jackson Laboratory