Mouse Genome Informatics
hm1
    Hoxdtm3Ddu/Hoxdtm3Ddu
involves: 129S2/SvPas * C57BL/6 * SJL
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
normal phenotype
• no obvious phenotype, no defect detected in reproductive or skeletal systems


Mouse Genome Informatics
cx2
    Hoxa11tm1Ssp/Hoxa11+
Hoxdtm3Ddu/Hoxd+

involves: 129S2/SvPas * C57BL/6 * CF-1 * SJL
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
skeleton
N
• normal morphology of the ulna, radius, tibia, and fibula (J:47900)


Mouse Genome Informatics
cx3
    Hoxa11tm1Ssp/Hoxa11+
Hoxdtm3Ddu/Hoxdtm3Ddu

involves: 129S2/SvPas * C57BL/6 * CF-1 * SJL
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
limbs/digits/tail
• lack of distal fusion of tibia and fibula
• lack of distal fusion of tibia and fibula

skeleton
• lack of distal fusion of tibia and fibula
• lack of distal fusion of tibia and fibula


Mouse Genome Informatics
cx4
    Hoxa11tm1Ssp/Hoxa11tm1Ssp
Hoxdtm3Ddu/Hoxdtm3Ddu

involves: 129S2/SvPas * C57BL/6 * CF-1 * SJL
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
limbs/digits/tail
• thickening of radius
• thickening of ulna
• lack of distal fusion of tibia and fibula
• thickening of fibula
• lack of distal fusion of tibia and fibula
• thickening of tibia

skeleton
• thickening of radius
• thickening of ulna
• lack of distal fusion of tibia and fibula
• thickening of fibula
• lack of distal fusion of tibia and fibula
• thickening of tibia


Mouse Genome Informatics
cx5
    Del(2Hoxd11-Hoxd13)29Ddu/Hoxdtm3Ddu
involves: 129S2/SvPas * C57BL/6 * SJL
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
limbs/digits/tail
• reductions in size of digits II and V