All Phenotypes Kitl<Sl-18H> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Kitl^Sl-18H
steel 18 Harwell
MGI:1856366

Summary

4 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Kitl^Sl-18H/Kitl^Sl-18H	involves: 101/H * C3H/HeH	MGI:3778061
ht2	Kitl^Sl-18H/Kitl⁺	involves: 101/H * C3H/HeH	MGI:3778060
ht3	Kitl^Sl-18H/Kitl^Sl-con	Not Specified	MGI:3778068
cx4	Kitl^Sl-18H/Kitl⁺ X/Sry^AKR/J	involves: AKR/J * C57BL/6J	MGI:3778817

Allelic Composition	Kitl^Sl-18H/Kitl^Sl-18H
Genetic Background	involves: 101/H * C3H/HeH

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Kitl^Sl-18H mutation (1 available); any Kitl mutation (92 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

embryonic lethality ( J:18280 )

embryonic lethality between implantation and somite formation ( J:18280 )

Allelic Composition	Kitl^Sl-18H/Kitl⁺
Genetic Background	involves: 101/H * C3H/HeH

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Kitl^Sl-18H mutation (1 available); any Kitl mutation (92 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

postnatal lethality, incomplete penetrance ( J:18280 )

• small, pale young seen at birth likely comprise the 40% loss of heterozygotes from heterozygous matings

pigmentation

diluted coat color ( J:18280 )

• greyish coat

head blaze ( J:18280 )

• in combination with Kitl^Sl-con there is a prominent white head blaze

white spotting ( J:18280 )

• head spotting and occasional nose and belly spotting

belly spot ( J:18280 )

• occasional belly spot

head spot ( J:18280 )

hypopigmentation ( J:18280 )

• ears and tail are pale

hematopoietic system

anemia ( J:18280 )

• pale offspring are presumed to be slightly anemic

integument

diluted coat color ( J:18280 )

• greyish coat

head blaze ( J:18280 )

• in combination with Kitl^Sl-con there is a prominent white head blaze

white spotting ( J:18280 )

• head spotting and occasional nose and belly spotting

belly spot ( J:18280 )

• occasional belly spot

head spot ( J:18280 )

pallor ( J:18280 )

Allelic Composition	Kitl^Sl-18H/Kitl^Sl-con
Genetic Background	Not Specified

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Kitl^Sl-18H mutation (1 available); any Kitl mutation (92 available)
Kitl^Sl-con mutation (1 available); any Kitl mutation (92 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

pigmentation

diluted coat color ( J:18280 )

• pale grey coat color

head blaze ( J:18280 )

• compound heterozygote displays a prominant white head blaze

integument

diluted coat color ( J:18280 )

• pale grey coat color

head blaze ( J:18280 )

• compound heterozygote displays a prominant white head blaze

Allelic Composition	Kitl^Sl-18H/Kitl⁺ X/Sry^AKR/J
Genetic Background	involves: AKR/J * C57BL/6J

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Kitl^Sl-18H mutation (1 available); any Kitl mutation (92 available)
Sry^AKR/J mutation (6 available); any Sry mutation (51 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

endocrine/exocrine glands

decreased testis weight ( J:133266 )

• Background Sensitivity: in the presence of Sry^AKR/J on a C57BL/6 background testes weight is less than normal

reproductive system

decreased testis weight ( J:133266 )

• Background Sensitivity: in the presence of Sry^AKR/J on a C57BL/6 background testes weight is less than normal

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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