Mouse Genome Informatics
hm1
    sy/sy
B6C3Fe-a/a
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
limbs/digits/tail
• variable penetrance, usually of digits 2 and 3 or 3 and 4, more rarely 2, 3 and 4; fusion of 2, 3 and 4 is more frequently seen on the hind paw than the fore paws

Mouse Models of Human Disease
OMIM IDRef(s)
NOT Arthrogryposis, Distal, Type 9; DA9 121050 J:68881


Mouse Genome Informatics
hm2
    sy/sy
Not Specified
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
mortality/aging
• within 1 month of birth

behavior/neurological

hearing/vestibular/ear
• thin semicircular canals
• development of excessive mesenchymal tissue followed by collapse of endolymphatic space and degeneration of membraneous labyrinth

limbs/digits/tail
• variable penetrance
• usually of digits 2 and 3 or 3 and 4

skeleton
• synostosis of phalanges
• variable penetrance


Mouse Genome Informatics
cx3
    Slc12a2sy-ns/sy
involves: C57BL/6 * MK/ReJ
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
behavior/neurological

hearing/vestibular/ear
• no discernible auditory brainstem responses (ABR) to maximum output stimuli at 99 dB
• profoundly deaf at 2-3 month of age