Agbl2^tm1.1Ics
Targeted Allele Detail

Summary

• Symbol: Agbl2^tm1.1Ics
• Name: ATP/GTP binding protein-like 2; targeted mutation 1.1, Mouse Clinical Institute
• MGI ID: MGI:8238062
• Gene: Agbl2 Location: Chr2:90613071-90664781 bp, + strand Genetic Position: Chr2, 50.37 cM
• Alliance: Agbl2^tm1.1Ics page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:215911
• Parent Cell Line: P1 (ES Cell)
• Strain of Origin: 129S2/SvPas

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: A loxP site was inserted into intron 8 and an FRT site flanked neomycin resistance gene cassette followed by a second loxP site were inserted into intron 9. The neo cassette was removed through subsequent Flp-mediated recombination, leaving a conditional-ready allele with exon 9 (ENSMUSE00001231910; GRCm39, Agbl2-201) floxed. (J:215911)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Agbl2 Mutation: 67 strains or lines available

References

• Original: J:215911 Tort O, et al., The cytosolic carboxypeptidases CCP2 and CCP3 catalyze posttranslational removal of acidic amino acids. Mol Biol Cell. 2014 Oct 1;25(19):3017-27
• All: 1 reference(s)