Bcor^em1(IMPC)Mbp
Endonuclease-mediated Allele Detail

Summary

• Symbol: Bcor^em1(IMPC)Mbp
• Name: BCL6 interacting corepressor; endonuclease-mediated mutation 1, Mouse Biology Program, UC Davis
• MGI ID: MGI:7867282
• Gene: Bcor Location: ChrX:11902979-12026594 bp, - strand Genetic Position: ChrX, 6.83 cM, cytoband A1.2
• Alliance: Bcor^em1(IMPC)Mbp page
• IMPC: Bcor gene page

Mutation origin

• Strain of Origin: C57BL/6NCrl
• Project Collection: IMPC

Mutation description

• Allele Type: Endonuclease-mediated (Not Applicable)
• Mutation: Intragenic deletion
• Mutation details: Six base pairs GGCGGA of the 5UTR were constitutively deleted using optimized CRISPR Cas9 KI technology utilizing Ribonucleoprotein (RNP) in the presence of a synthetic single strand DNA repair template harboring the desired KI. The KI contains a 6 bp deletion, which ablates positions 1-16 of protospacer and will protect the HDR derived locus from re-cutting by Cas9. (J:94077)
• Inheritance: Not Specified

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Bcor Mutation: 18 strains or lines available

References

• Original: J:94077 Mutant Mouse Regional Resource Centers, Information obtained from the Mutant Mouse Regional Resource Centers (MMRRC). Unpublished. 2004-2015
• All: 1 reference(s)