Serping1^em3Cya
Endonuclease-mediated Allele Detail

Summary

• Symbol: Serping1^em3Cya
• Name: serine (or cysteine) peptidase inhibitor, clade G, member 1; endonuclease-mediated mutation 3, Cyagen Biosciences
• MGI ID: MGI:7797862
• Gene: Serping1 Location: Chr2:84595704-84605748 bp, - strand Genetic Position: Chr2, 49.45 cM
• Alliance: Serping1^em3Cya page

Mutation origin

• Strain of Origin: C57BL/6JCya

Mutation description

• Allele Type: Endonuclease-mediated (Modified isoform(s))
• Mutation: Intragenic deletion
• Mutation details: CRISPR-targeting knocked outa partial sequence (c.159_168 TCCCCCAGAG) in exon 3. This allele is a gene knockout, where the Serping1 gene homologous to the human gene has been knocked out. In Serping1 KO allele, C1-INH protein is deficient. (J:326541)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Serping1 Mutation: 29 strains or lines available

References

• Original: J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022
• All: 1 reference(s)