Rr350^em1Mirka
Endonuclease-mediated Allele Detail

Summary

• Symbol: Rr350^em1Mirka
• Name: regulatory region 350; endonuclease-mediated mutation 1, Mira Kassouf
• MGI ID: MGI:7714615
• Synonyms: deltaalpha-SE
• Gene: Rr350 Location: Chr11:32195540-32219344 bp Genetic Position: Chr11, Syntenic
• Alliance: Rr350^em1Mirka page

Mutation origin

• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Endonuclease-mediated (Modified regulatory region)
• Mutations: Intergenic deletion, Intragenic deletion
• Mutation details : Hematopoietic Hba enhancer R2 ( Rr350 tm1.1Mirka allele (where enhancers R1 ( Rr351 ), Rm ( Rr353 ), all part of super-enhancer Find Mice (IMSR):
  • Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
  • Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
  • Carrying any Rr350 Mutation: 0 strains or lines available
• References:
  • Original: J:344222 Blayney JW, et al., Super-enhancers include classical enhancers and facilitators to fully activate gene expression. Cell. 2023 Dec 21;186(26):5826-5839.e18
  • All: 1 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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