Mirc11^tm1.1Akit
Targeted Allele Detail

Summary

• Symbol: Mirc11^tm1.1Akit
• Name: microRNA cluster 11, including Mir23a through Mir24-2; targeted mutation 1.1, Takayuki Akimoto
• MGI ID: MGI:7705323
• Gene: Mirc11 Location: Chr8:84935147-84935550 bp Genetic Position: Chr8, Syntenic

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:267179
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: LoxP sites were inserted around Mir23a, Mir27a and Mir24-2 and an FRT flanked neo cassette and third loxP site were also inserted. Flp mediated recombination removed the neo cassette. (J:267179)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mirc11 Mutation: 2 strains or lines available

References

• Original: J:267179 Oikawa S, et al., Role of endothelial microRNA-23 clusters in angiogenesis in vivo. Am J Physiol Heart Circ Physiol. 2018 Oct 1;315(4):H838-H846
• All: 3 reference(s)