Nrxn1^tm1Mami
Targeted Allele Detail

Summary

• Symbol: Nrxn1^tm1Mami
• Name: neurexin I; targeted mutation 1, Markus Missler
• MGI ID: MGI:7660972
• Gene: Nrxn1 Location: Chr17:90341059-91400499 bp, - strand Genetic Position: Chr17, 59.73 cM
• Alliance: Nrxn1^tm1Mami page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:349905
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: A loxP site was introduced upstream of the first coding exon and a neomycin resistance gene and second loxP site were introduced downstream of the second coding exon. (J:349905)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Nrxn1 Mutation: 102 strains or lines available

References

• Original: J:349905 Brockhaus J, et al., Conditional Knockout of Neurexins Alters the Contribution of Calcium Channel Subtypes to Presynaptic Ca(2+) Influx. Cells. 2024 Jun 5;13(11)
• All: 1 reference(s)