Hhip^em1H
Endonuclease-mediated Allele Detail

Summary

• Symbol: Hhip^em1H
• Name: Hedgehog-interacting protein; endonuclease-mediated mutation 1, Harwell
• MGI ID: MGI:7647216
• Gene: Hhip Location: Chr8:80692480-80784635 bp, - strand Genetic Position: Chr8, 37.95 cM, cytoband C3
• Alliance: Hhip^em1H page

Mutation origin

• Strain of Origin: C57BL/6NTac

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: This is a CRISPR/Cas9 induced mutation deleting 1061 nucleotides from Hhip gene, across critical exons ENSMUSE00000212344 and ENSMUSE00000464439, to introduce a frameshift that results in a premature stop codon/null allele. (J:361968)
• Inheritance: Not Specified

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Hhip Mutation: 43 strains or lines available

References

• Original: J:361968 Mary Lyon Centre at MRC Harwell, Direct data submission from Mary Lyon Centre at MRC Harwell. 2025
• All: 1 reference(s)