Prdm14^em1Utr
Endonuclease-mediated Allele Detail

Summary

• Symbol: Prdm14^em1Utr
• Name: PR domain containing 14; endonuclease-mediated mutation 1, University of Tsukuba Laboratory Animal Resource Center
• MGI ID: MGI:7639915
• Synonyms: Prdm14 KO
• Gene: Prdm14 Location: Chr1:13183681-13197387 bp, - strand Genetic Position: Chr1, 4.1 cM
• Alliance: Prdm14^em1Utr page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Exon 6 was deleted using sgRNAs targeting introns 5 and 6 with CRISPR/Cas9 technology. (J:317830)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Prdm14 Mutation: 51 strains or lines available

References

• Original: J:317830 Kuno A, et al., DAJIN enables multiplex genotyping to simultaneously validate intended and unintended target genome editing outcomes. PLoS Biol. 2022 Jan;20(1):e3001507
• All: 1 reference(s)