Tg(CAG-Phlp5*,-EGFP)304Biat
Transgene Detail

Summary

• Symbol: Tg(CAG-Phlp5*,-EGFP)304Biat
• Name: transgene insertion 304, Biomodels Austria
• MGI ID: MGI:7571206
• Synonyms: Tg(Phlp5-GFP)304Biat
• Transgene: Tg(CAG-Phlp5*,-EGFP)304Biat Location: unknown
• Alliance: Tg(CAG-Phlp5*,-EGFP)304Biat page

Transgene origin

• Strain of Origin: BALB/c

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence, Reporter)
• Mutation: Insertion
• Mutation details: The cDNA of one major clinically relevant allergen of Timothy grass/Phleum pratense (Phl p 5) was fused to a transmembrane domain and a leader peptide (described in Baranyi et al., J Immunol 2008, 180: 8168-8175) and cloned into pcall2 IRES eGFP vector, under control of a chicken beta globulin promoter and CMV enhancer. (J:310820)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:310820 Baranyi U, et al., Cell Therapy for Prophylactic Tolerance in Immunoglobulin E-mediated Allergy. EBioMedicine. 2016 May;7:230-9
• All: 1 reference(s)