Mettl8^em1Hsng
Endonuclease-mediated Allele Detail

Summary

• Symbol: Mettl8^em1Hsng
• Name: methyltransferase 8, methylcytidine; endonuclease-mediated mutation 1, Hongjun Song
• MGI ID: MGI:7570096
• Synonyms: Mettl8^flox
• Gene: Mettl8 Location: Chr2:70794905-70885927 bp, - strand Genetic Position: Chr2, 42.34 cM
• Alliance: Mettl8^em1Hsng page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready)
• Mutation: Insertion
• Guide RNAs were designed to insert loxP sites flanking exon 3 (92 bp). (J:334113)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Mettl8 Mutation: 45 strains or lines available

References

• Original: J:334113 Zhang F, et al., Epitranscriptomic regulation of cortical neurogenesis via Mettl8-dependent mitochondrial tRNA m(3)C modification. Cell Stem Cell. 2023 Mar 2;30(3):300-311.e11
• All: 1 reference(s)