Mertk^em1Wsch
Endonuclease-mediated Allele Detail

Summary

• Symbol: Mertk^em1Wsch
• Name: MER proto-oncogene tyrosine kinase; endonuclease-mediated mutation 1, Won-Suk Chung
• MGI ID: MGI:7548594
• Synonyms: Mertk^fl
• Gene: Mertk Location: Chr2:128540876-128644814 bp, + strand Genetic Position: Chr2, 62.63 cM
• Alliance: Mertk^em1Wsch page

Mutation origin

• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready, No functional change)
• Mutation: Insertion
• CRISPR-targeting floxed exon 2. (J:314434)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mertk Mutation: 63 strains or lines available

References

• Original: J:314434 Park J, et al., Microglial MERTK eliminates phosphatidylserine-displaying inhibitory post-synapses. EMBO J. 2021 Aug 2;40(15):e107121
• All: 2 reference(s)