Rarres2^em1.1Xwan
Endonuclease-mediated Allele Detail

Summary

• Symbol: Rarres2^em1.1Xwan
• Name: retinoic acid receptor responder (tazarotene induced) 2; endonuclease-mediated mutation 1.1, Xiaohui Wang
• MGI ID: MGI:7548519
• Synonyms: chemerin flox
• Gene: Rarres2 Location: Chr6:48546630-48549723 bp, - strand Genetic Position: Chr6, 23.55 cM
• Alliance: Rarres2^em1.1Xwan page

Mutation origin

• Strain of Origin: Not Applicable

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of exon 1 and an FRT-flanked PGK-neomycin cassette and second loxP site were inserted downstream of exon 3 via CRISRP/Cas9 techology. The neomycin cassette was removed via flp-mediated recombination. (J:342422)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rarres2 Mutation: 12 strains or lines available

References

• Original: J:342422 Lin X, et al., Aerobic exercise-induced decrease of chemerin improved glucose and lipid metabolism and fatty liver of diabetes mice through key metabolism enzymes and proteins. Biochim Biophys Acta Mol Cell Biol Lipids. 2023 Dec;1868(12):159409
• All: 1 reference(s)