Zfp503^tm1.1Bpb
Targeted Allele Detail

Summary

• Symbol: Zfp503^tm1.1Bpb
• Name: zinc finger protein 503; targeted mutation 1.1, Brian P Brooks
• MGI ID: MGI:7536898
• Synonyms: Zfp503^-
• Gene: Zfp503 Location: Chr14:22034030-22039669 bp, - strand Genetic Position: Chr14, 12.0 cM
• Alliance: Zfp503^tm1.1Bpb page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:331141
• Parent Cell Line: W4 (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The sequence spanning exon 2 and exon 3 of the Zfp503 was replaced by a beta-galactosidase-pGK-Neo cassette. The floxed Neo cassette was removed by cre recombinase. (J:290119, J:331141)

Expression

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Zfp503 Mutation: 36 strains or lines available

References

• Original: J:331141 Boobalan E, et al., Zfp503/Nlz2 Is Required for RPE Differentiation and Optic Fissure Closure. Invest Ophthalmol Vis Sci. 2022 Nov 1;63(12):5
• All: 2 reference(s)