Wtap^em1Chez
Endonuclease-mediated Allele Detail

Summary

• Symbol: Wtap^em1Chez
• Name: WT1 associating protein; endonuclease-mediated mutation 1, Zheng Chen
• MGI ID: MGI:7532764
• Synonyms: Wtap^flox
• Gene: Wtap Location: Chr17:13185686-13211430 bp, - strand Genetic Position: Chr17, 8.73 cM
• Alliance: Wtap^em1Chez page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready)
• Mutation: Insertion
• Using the CRISPR-Cas9 technique, two loxp sites flanking the exon 4 of the Wtap gene were inserted. (J:330788, J:337787)

Expression

In Mice Carrying this Mutation:

4 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Wtap Mutation: 81 strains or lines available

References

• Original: J:337787 Wang Y, et al., WTAP regulates postnatal development of brown adipose tissue by stabilizing METTL3 in mice. Life Metabolism. 2022;1(3):270-284
• All: 4 reference(s)