Gt(ROSA)26Sor^{tm1(Myocd)Jomm}
Targeted Allele Detail

Summary

• Symbol: Gt(ROSA)26Sor^{tm1(Myocd)Jomm}
• Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Joseph M Miano
• MGI ID: MGI:7529625
• Synonyms: iMyocd
• Gene: Gt(ROSA)26Sor Location: Chr6:113044389-113054205 bp, - strand Genetic Position: Chr6, 52.73 cM
• Alliance: Gt(ROSA)26Sor^{tm1(Myocd)Jomm} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:340471
• Parent Cell Line: G4 (ES Cell)
• Strain of Origin: (129S6/SvEvTac x C57BL/6NCrl)F1

Mutation description

• Allele Type: Targeted (Conditional ready, Epitope tag, Inserted expressed sequence)
• Mutation: Insertion
• Gt(ROSA)26Sor^{tm1(Myocd)Jomm} expresses 1 gene
  Knock-in expresses:
  

  Organism	Expressed Gene	Note
  mouse	Myocd (MGI:2137495)

• An HA-tagged Myocd cDNA cloned downstream of a CAG-driven stop-floxed cassette in the Rosa26 locus. (J:340471)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gt(ROSA)26Sor Mutation: 1098 strains or lines available

References

• Original: J:340471 Warthi G, et al., Generation and Comparative Analysis of an Itga8-CreER (T2) Mouse with Preferential Activity in Vascular Smooth Muscle Cells. Nat Cardiovasc Res. 2022 Nov;1(11):1084-1100
• All: 1 reference(s)