Tg(Myh6-Kcnj8*S422L)105Hnky
Transgene Detail

Summary

• Symbol: Tg(Myh6-Kcnj8*S422L)105Hnky
• Name: transgene insertion 105, Haruaki Nakaya
• MGI ID: MGI:7523965
• Transgene: Tg(Myh6-Kcnj8*S422L)105Hnky Location: unknown
• Alliance: Tg(Myh6-Kcnj8*S422L)105Hnky page

Transgene origin

• Strain of Origin: C57BL/6

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Myh6-Kcnj8*S422L)105Hnky expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  rat

  Kcnj8 (25472)

  Kcnj8

  (MGI:1100508)

  S422L mutation

• Tg(Myh6-Kcnj8*S422L)105Hnky expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Myh6 (MGI:97255)

• Mutation details: The transgene expressing the rat mutated Kcnj8 (S422L) under the control of mouse Myh6 (myosin, heavy polypeptide 6, cardiac muscle, alpha) promoter. (J:287787)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:287787 Watanabe Y, et al., Electrophysiological analyses of transgenic mice overexpressing KCNJ8 with S422L mutation in cardiomyocytes. J Pharmacol Sci. 2017 Sep;135(1):37-43
• All: 2 reference(s)