Hes7^tm3.1Kag
Targeted Allele Detail

Summary

• Symbol: Hes7^tm3.1Kag
• Name: hes family bHLH transcription factor 7; targeted mutation 3.1, Ryoichiro Kageyama
• MGI ID: MGI:7522456
• Synonyms: Hes7deltaIn
• Gene: Hes7 Location: Chr11:69011230-69014881 bp, + strand Genetic Position: Chr11, 42.38 cM
• Alliance: Hes7^tm3.1Kag page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:278608
• Parent Cell Line: TT2 (ES Cell)
• Strain of Origin: (C57BL/6NCrlj x CBA/JNCrlj)F1

Mutation description

• Allele Type: Targeted (Not Specified)
• Mutation: Intragenic deletion
• Mutation details: The intron sequence of Hes7 were removed. The The floxed neo cassette was removed by transient expression of cre recombinase. (J:278608)

Expression

In Mice Carrying this Mutation:

10 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Hes7 Mutation: 22 strains or lines available

References

• Original: J:278608 Takashima Y, et al., Intronic delay is essential for oscillatory expression in the segmentation clock. Proc Natl Acad Sci U S A. 2011 Feb 22;108(8):3300-5
• All: 1 reference(s)