Ctbp2^em1Hshim
Endonuclease-mediated Allele Detail

Summary

• Symbol: Ctbp2^em1Hshim
• Name: C-terminal binding protein 2; endonuclease-mediated mutation 1, Hitoshi Shimano
• MGI ID: MGI:7519117
• Synonyms: CtBP2 flox
• Gene: Ctbp2 Location: Chr7:132589292-132726083 bp, - strand Genetic Position: Chr7, 76.32 cM
• Alliance: Ctbp2^em1Hshim page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready)
• Mutation: Insertion
• Mutation details: CRISPR/Cas9 genome editing technology was used to insert loxP sites into intron 4 and intron 6 of the gene. Exons 5 and 6 are flanked by loxP sites. (J:314743)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ctbp2 Mutation: 572 strains or lines available

References

• Original: J:314743 Sekiya M, et al., The transcriptional corepressor CtBP2 serves as a metabolite sensor orchestrating hepatic glucose and lipid homeostasis. Nat Commun. 2021 Nov 2;12(1):6315
• All: 2 reference(s)