Iqgap3^tm1.1Itoy
Targeted Allele Detail

Summary

• Symbol: Iqgap3^tm1.1Itoy
• Name: IQ motif containing GTPase activating protein 3; targeted mutation 1.1, Yoshiaki Ito
• MGI ID: MGI:7461832
• Synonyms: Iqgap3-2A-tdTomato
• Gene: Iqgap3 Location: Chr3:87989309-88028355 bp, + strand Genetic Position: Chr3, 38.78 cM
• Alliance: Iqgap3^tm1.1Itoy page
• IMPC: Iqgap3 gene page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:334620
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified
• Project Collection: NorCOMM

Mutation description

• Allele Type: Targeted (Reporter)
• Mutation: Insertion
• Mutation details: The 2A-tdTomato sequence was inserted before the stop codon in exon 38 of the Iqgap3 gene. The neo-selection cassette was self-deleted. (J:334620)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Iqgap3 Mutation: 82 strains or lines available

References

• Original: J:334620 Matsuo J, et al., Iqgap3-Ras axis drives stem cell proliferation in the stomach corpus during homoeostasis and repair. Gut. 2021 Oct;70(10):1833-1846
• All: 1 reference(s)