Asprv1^tm1Amag
Targeted Allele Detail

Summary

• Symbol: Asprv1^tm1Amag
• Name: aspartic peptidase, retroviral-like 1; targeted mutation 1, Masayuki Amagai
• MGI ID: MGI:7461823
• Synonyms: EGFP^SG1
• Gene: Asprv1 Location: Chr6:86605216-86606692 bp, + strand Genetic Position: Chr6, 37.75 cM
• Alliance: Asprv1^tm1Amag page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:309472
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The open reading frame of the gene was replaced with an EGFP gene and a floxed pgk-neo cassette via homologous recombination. GFP is expressed exclusively in the epidermal SG1 layer. (J:309472)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Asprv1 Mutation: 23 strains or lines available

References

• Original: J:309472 Matsui T, et al., A unique mode of keratinocyte death requires intracellular acidification. Proc Natl Acad Sci U S A. 2021 Apr 27;118(17):e2020722118
• All: 1 reference(s)