Foxg1^tm4144.1Tac
Targeted Allele Detail

Summary

• Symbol: Foxg1^tm4144.1Tac
• Name: forkhead box G1; targeted mutation 4144.1, Taconic
• MGI ID: MGI:7425324
• Gene: Foxg1 Location: Chr12:49429666-49433650 bp, + strand Genetic Position: Chr12, 21.78 cM
• Alliance: Foxg1^tm4144.1Tac page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:329946
• Parent Cell Line: iTL IC1 (ES Cell)
• Strain of Origin: C57BL/6NTac

Mutation description

• Allele Type: Targeted (Conditional ready, Epitope tag, Null/knockout)
• Mutation: Insertion
• Mutation details: The targeting construct inserted a loxP site, splice acceptor, STOP cassette, FRT-flanked neomycin resistance cassette, and loxP site after exon 1 and a triple HA tag at the C-terminus of the coding sequence. Flp-mediated recombination removed the selection cassette. (J:329946)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Foxg1 Mutation: 28 strains or lines available

References

• Original: J:329946 Erickson KR, et al., Behavioral and brain anatomical analysis of Foxg1 heterozygous mice. PLoS One. 2022;17(10):e0266861
• All: 1 reference(s)