Bcor^tm2Vjba
Targeted Allele Detail

Summary

• Symbol: Bcor^tm2Vjba
• Name: BCL6 interacting corepressor; targeted mutation 2, Vivian J Bardwell
• MGI ID: MGI:7398100
• Synonyms: Bcor^Neo
• Gene: Bcor Location: ChrX:11902979-12026594 bp, - strand Genetic Position: ChrX, 6.83 cM, cytoband A1.2
• Alliance: Bcor^tm2Vjba page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:329334
• Parent Cell Line: CJ7 (ES Cell)
• Strain of Origin: 129S1/Sv-Oca2⁺ Tyr⁺ Kitl⁺

Mutation description

• Allele Type: Targeted (Conditional ready, Null/knockout)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of exon 3 and an FRT-flanked PGK-Neomycin and second loxP site were inserted downstream of exon 3. (J:329334)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Bcor Mutation: 18 strains or lines available

References

• Original: J:329334 Wamstad JA, et al., Role of the transcriptional corepressor Bcor in embryonic stem cell differentiation and early embryonic development. PLoS One. 2008 Jul 30;3(7):e2814
• All: 1 reference(s)