Rorc^em1Bcgen
Endonuclease-mediated Allele Detail

Summary

• Symbol: Rorc^em1Bcgen
• Name: RAR-related orphan receptor gamma; endonuclease-mediated mutation 1, Biocytogen LLC
• MGI ID: MGI:7382782
• Synonyms: RORgammat^K256R
• Gene: Rorc Location: Chr3:94280106-94305583 bp, + strand Genetic Position: Chr3, 40.56 cM, cytoband F2
• Alliance: Rorc^em1Bcgen page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Endonuclease-mediated (Not Specified)
• Mutation: Nucleotide substitutions
• K256R point-mutation in the Rorc gene was designed and generated. (J:330635)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rorc Mutation: 42 strains or lines available

References

• Original: J:330635 Zhong X, et al., Decoupling the role of RORgammat in the differentiation and effector function of TH17 cells. Sci Adv. 2022 Oct 21;8(42):eadc9221
• All: 2 reference(s)