Depp1^em1Cya
Endonuclease-mediated Allele Detail

Summary

• Symbol: Depp1^em1Cya
• Name: DEPP1 autophagy regulator; endonuclease-mediated mutation 1, Cyagen Biosciences
• MGI ID: MGI:7316472
• Synonyms: Depp^-
• Gene: Depp1 Location: Chr6:116627645-116629808 bp, + strand Genetic Position: Chr6, 53.83 cM
• Alliance: Depp1^em1Cya page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: TALEN technology targeting exon 2 generated a 5 bp (AAATG) deletion resulting in a frameshift mutation. (J:326566)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Depp1 Mutation: 20 strains or lines available

References

• Original: J:326566 Guo F, et al., DEPP Deficiency Contributes to Browning of White Adipose Tissue. Int J Mol Sci. 2022 Jun 12;23(12)
• All: 1 reference(s)