Tnfrsf18^{tm1(TNFRSF18)Smoc}
Targeted Allele Detail

Summary

• Symbol: Tnfrsf18^{tm1(TNFRSF18)Smoc}
• Name: tumor necrosis factor receptor superfamily, member 18; targeted mutation 1, Shanghai Model Organisms Center
• MGI ID: MGI:7292879
• Synonyms: Tnfrsf18^{tm1(hGITR)Smoc}
• Gene: Tnfrsf18 Location: Chr4:156110779-156113351 bp, + strand Genetic Position: Chr4, 87.76 cM, cytoband E
• Alliance: Tnfrsf18^{tm1(TNFRSF18)Smoc} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:238766
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: BALB/c

Mutation description

• Allele Type: Targeted (Humanized sequence, Inserted expressed sequence)
• Mutations: Insertion, Intragenic deletion
• Tnfrsf18^{tm1(TNFRSF18)Smoc} expresses 1 gene
  Knock-in expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  TNFRSF18 (8784)

  Tnfrsf18

  (MGI:894675)

• Mutation details: The endogenous mice Tnfrsf18 gene was replaced by human GITR gene. While hGITR(BALB/c)(Stock No.NM-HU-2000045) mice function similarly to hGITR(BALB/c,2) mice, for more detailed information please contact our technical advisor. (J:238766)
• Inheritance: Not Specified

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tnfrsf18 Mutation: 30 strains or lines available

References

• Original: J:238766 Shanghai Model Organisms Center, Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China. MGI Direct Data Submission. 2017
• All: 1 reference(s)