Cd36^em1Cya
Endonuclease-mediated Allele Detail

Summary

• Symbol: Cd36^em1Cya
• Name: CD36 molecule; endonuclease-mediated mutation 1, Cyagen Biosciences
• MGI ID: MGI:7286488
• Synonyms: Cd36^em1cyagen
• Gene: Cd36 Location: Chr5:17986688-18093799 bp, - strand Genetic Position: Chr5, 8.11 cM
• Alliance: Cd36^em1Cya page

Mutation origin

• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR/Cas9 technology targeted exons 5 to 9 for deletion. (J:325546)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cd36 Mutation: 33 strains or lines available

References

• Original: J:325546 Zhang Y, et al., Oxidized high-density lipoprotein promotes CD36 palmitoylation and increases lipid uptake in macrophages. J Biol Chem. 2022 Apr 29;298(6):102000
• All: 1 reference(s)