Mirc34^tm1Mkss
Targeted Allele Detail

Summary

• Symbol: Mirc34^tm1Mkss
• Name: microRNA cluster 34, including Mir449a through Mir449c; targeted mutation 1, Michael Kessel
• MGI ID: MGI:7266286
• Synonyms: miR-449 loxP
• Gene: Mirc34 Location: unknown Genetic Position: Chr13, Syntenic

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:223064
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of Mir449c. A floxed neomycin resistance cassette with a 3' loxP site was inserted downstream of Mir449a. (J:223064)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mirc34 Mutation: 2 strains or lines available

References

• Original: J:223064 Song R, et al., miR-34/449 miRNAs are required for motile ciliogenesis by repressing cp110. Nature. 2014 Jun 5;510(7503):115-20
• All: 2 reference(s)