C2cd6^em1Chng
Endonuclease-mediated Allele Detail

Summary

• Symbol: C2cd6^em1Chng
• Name: C2 calcium dependent domain containing 6; endonuclease-mediated mutation 1, Jean-Ju Chung
• MGI ID: MGI:7255011
• Synonyms: CatSpert^134del, CatSpert^delta, CatSpert^tm1CHNG
• Gene: C2cd6 Location: Chr1:59036275-59134059 bp, - strand Genetic Position: Chr1, 29.2 cM, cytoband C2
• Alliance: C2cd6^em1Chng page

Mutation origin

• Strain of Origin: C57BL/6NCrl

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR-targeting deleted 134 bp resulting in a frameshift and premature termination. (J:321418)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any C2cd6 Mutation: 37 strains or lines available

References

• Original: J:321418 Hwang JY, et al., C2cd6-encoded CatSpertau targets sperm calcium channel to Ca(2+) signaling domains in the flagellar membrane. Cell Rep. 2022 Jan 18;38(3):110226
• All: 1 reference(s)