Larp7^em1Bgzg
Endonuclease-mediated Allele Detail

Summary

• Symbol: Larp7^em1Bgzg
• Name: La ribonucleoprotein 7, transcriptional regulator; endonuclease-mediated mutation 1, Bing Zhang
• MGI ID: MGI:6888223
• Gene: Larp7 Location: Chr3:127330363-127346998 bp, - strand Genetic Position: Chr3, 56.54 cM, cytoband H1
• Alliance: Larp7^em1Bgzg page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR-targeting deleted exons 2 and 3. This deletion leaves Mir302 and Mir367 intact. (J:321746)

Expression

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Larp7 Mutation: 38 strains or lines available

References

• Original: J:321746 Yu H, et al., LARP7 Protects Against Heart Failure by Enhancing Mitochondrial Biogenesis. Circulation. 2021;143(20):2007-2022
• All: 3 reference(s)