Arrb1^tm1.1Gpe
Targeted Allele Detail

Summary

• Symbol: Arrb1^tm1.1Gpe
• Name: arrestin, beta 1; targeted mutation 1.1, Gang Pei
• MGI ID: MGI:6864164
• Gene: Arrb1 Location: Chr7:99184673-99255978 bp, + strand Genetic Position: Chr7, 54.09 cM
• Alliance: Arrb1^tm1.1Gpe page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:253840
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: An FRT-flanked neomycin cassette and a loxP site were inserted upstream of exon 2 and a second loxP site was inserted downstream of exon 3. Exons 2 and 3 were deleted via cre-mediated recombination. This allele contains the neomycin cassette. (J:253840)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Arrb1 Mutation: 30 strains or lines available

References

• Original: J:253840 Wang C, et al., beta-arrestin-1 contributes to brown fat function and directly interacts with PPARalpha and PPARgamma. Sci Rep. 2016 Jun 15;6:26999
• All: 2 reference(s)