Sod1^{em1(SOD1)Emcf}
Endonuclease-mediated Allele Detail

Summary

• Symbol: Sod1^{em1(SOD1)Emcf}
• Name: superoxide dismutase 1, soluble; endonuclease-mediated mutation 1, Elizabeth MC Fisher
• MGI ID: MGI:6856511
• Synonyms: HU-SOD1-FLOX-A4V-EM1-B6
• Gene: Sod1 Location: Chr16:90017650-90023221 bp, + strand Genetic Position: Chr16, 51.56 cM, cytoband B5-C3
• Alliance: Sod1^{em1(SOD1)Emcf} page

Mutation origin

• Strain of Origin: B6.129-Sod1^{tm1.1(SOD1)Emcf}/H

Mutation description

• Allele Type: Endonuclease-mediated (Inserted expressed sequence)
• Mutation: Insertion
• Sod1^{em1(SOD1)Emcf} expresses 1 gene
  Knock-in expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  SOD1 (6647)

  Sod1	(MGI:98351)

  NM_000454.4(SOD1):c.14CtoT (p.Ala5Val)

• Mutation details: CRISPR-targeting introduced a missense mutation (commonly called A4V; NM_000454.4(SOD1):c.14CtoT (p.Ala5Val)) into Sod1^{tm1.1(SOD1)Emcf}. (J:361968)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 4 strains available Cell Lines: 0 lines available
• Carrying any Sod1 Mutation: 49 strains or lines available

References

• Original: J:361968 Mary Lyon Centre at MRC Harwell, Direct data submission from Mary Lyon Centre at MRC Harwell. 2025
• All: 1 reference(s)