Mirc13^tm1Jko
Targeted Allele Detail

Summary

• Symbol: Mirc13^tm1Jko
• Name: microRNA cluster 13, including Mir141 through Mir200c; targeted mutation 1, Keio University School of Medicine, Japan
• MGI ID: MGI:6832828
• Gene: Mirc13 Location: Chr6:124694877-124695353 bp Genetic Position: Chr6, Syntenic

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:314615
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The targeting construct replaced the microRNA sequence with a neomycin resistance cassette flanked by a lox71 site and an FRT site. (J:314615)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mirc13 Mutation: 3 strains or lines available

References

• Original: J:314615 Xu C, et al., Maternal diabetes induces senescence and neural tube defects sensitive to the senomorphic rapamycin. Sci Adv. 2021 Jun;7(27)
• All: 1 reference(s)