Fam3a^tm1.1Cya
Targeted Allele Detail

Summary

• Symbol: Fam3a^tm1.1Cya
• Name: FAM3 metabolism regulating signaling molecule A; targeted mutation 1.1, Cyagen Biosciences
• MGI ID: MGI:6760587
• Synonyms: FAM3A-Loxp, Fam3a^tm1.1Cgen
• Gene: Fam3a Location: ChrX:73428325-73436878 bp, - strand Genetic Position: ChrX, 38.0 cM, cytoband A6
• Alliance: Fam3a^tm1.1Cya page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:304073
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: A loxp site was inserted into the intron before exon4 and another loxp site followed by Frt flanked neo selection cassette was inserted into the intron after the exon 8 of the mouse Fam3a gene. The neo cassette was excised by flp recombinase. (J:304073, J:309781)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Fam3a Mutation: 6 strains or lines available

References

• Original: J:304073 Yang W, et al., FAM3A plays crucial roles in controlling PDX1 and insulin expressions in pancreatic beta cells. FASEB J. 2020 Mar;34(3):3915-3931
• All: 2 reference(s)