Stab1^tm1.2Jbae
Targeted Allele Detail

Summary

• Symbol: Stab1^tm1.2Jbae
• Name: stabilin 1; targeted mutation 1.2, Jong-Sup Bae
• MGI ID: MGI:6755493
• Gene: Stab1 Location: Chr14:30860970-30890598 bp, - strand Genetic Position: Chr14, 19.09 cM
• Alliance: Stab1^tm1.2Jbae page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:302035
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exons 2 to 5 were flanked by loxP sites. A PGK-neomycin cassette flanked by FRT sites inserted upstream of exon 2 and was removed via Flp-mediated recombination. Cre-mediated recombination deleted exons 2 to 5. (J:302035)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Stab1 Mutation: 125 strains or lines available

References

• Original: J:302035 Lee W, et al., Macrophagic Stabilin-1 Restored Disruption of Vascular Integrity Caused by Sepsis. Thromb Haemost. 2018 Oct;118(10):1776-1789
• All: 3 reference(s)