Tg(FUS*P525L)1Kt
Transgene Detail

Summary

• Symbol: Tg(FUS*P525L)1Kt
• Name: transgene insertion 1, Kevin Talbot
• MGI ID: MGI:6751616
• Synonyms: Tg(FUS-P525L)1Kt
• Transgene: Tg(FUS*P525L)1Kt Location: unknown
• Alliance: Tg(FUS*P525L)1Kt page

Transgene origin

• Strain of Origin: (C57BL/6 x CBA)F1

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(FUS*P525L)1Kt expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  FUS (2521)

  Fus	(MGI:1353633)

  with the amino acid substitution P525L

• Mutation details: The transgene contains the human genomic FUS locus from a 225 kb BAC, RP11-388M20 (BACPAC resource centre, Childrens Hospital Oakland Research Institute) with loxP sites, and an mCherry reporter gene. The exon 15 mutation (c. 1574C-T) was inserted separately by site-directed mutagenesis. Lines 1 and 3 were generated. (J:82809)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:82809 European Mouse Mutant Archive, Information obtained from the European Mouse Mutant Archive (EMMA). Unpublished. 2003-2013
• All: 1 reference(s)