Myct1^tm1.1Cya
Targeted Allele Detail

Summary

• Symbol: Myct1^tm1.1Cya
• Name: myc target 1; targeted mutation 1.1, Cyagen Biosciences
• MGI ID: MGI:6696431
• Synonyms: Myct1^f, Myct1^tm1.1Cgen
• Gene: Myct1 Location: Chr10:5543728-5556789 bp, + strand Genetic Position: Chr10, 1.99 cM, cytoband A1
• Alliance: Myct1^tm1.1Cya page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:303692
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: LoxP sites were inserted in front of exon 2 and immediately after the termination codon. In addition, an FRT-flanked neomycin resistance selection cassette was inserted and removed via Flp-mediated recombination. (J:303692)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Myct1 Mutation: 13 strains or lines available

References

• Original: J:303692 Kabir AU, et al., Dual role of endothelial Myct1 in tumor angiogenesis and tumor immunity. Sci Transl Med. 2021 Mar 3;13(583)
• All: 1 reference(s)