Del(3Dcst1-Dcst2)1Nino
Endonuclease-mediated Allele Detail

Summary

• Symbol: Del(3Dcst1-Dcst2)1Nino
• Name: deletion, Chr3, Naokazu Inoue 1
• MGI ID: MGI:6696424
• Synonyms: Dcst1/2 KO
• Gene: Del(3Dcst1-Dcst2)1Nino Location: unknown Genetic Position: Chr3, Syntenic

Mutation origin

• Strain of Origin: 129

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Del(3Dcst1-Dcst2)1Nino involves 2 genes/genome features (Dcst1, Dcst2) View all
• Mutation details: CRISPR-targeting replaced exons 1-4 of Dcst2 and exons 3 of Dcst1 with a neomycin resistance cassette. (J:304712)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Del(3Dcst1-Dcst2)1Nino Mutation: 0 strains or lines available

References

• Original: J:304712 Inoue N, et al., Evolutionarily conserved sperm factors, DCST1 and DCST2, are required for gamete fusion. Elife. 2021 Apr 19;10:e66313
• All: 1 reference(s)