Qki^tm1Zfl
Targeted Allele Detail

Summary

• Symbol: Qki^tm1Zfl
• Name: quaking, KH domain containing RNA binding; targeted mutation 1, Zi-Fan Lu
• MGI ID: MGI:6690705
• Synonyms: QKI-floxed, QKI LoxP
• Gene: Qki Location: Chr17:10425480-10538706 bp, - strand Genetic Position: Chr17, 7.75 cM
• Alliance: Qki^tm1Zfl page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:283454
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• LoxP sites and an frt-flanked neomycin selection cassette were inserted to flank exon 2, (J:283454)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Qki Mutation: 26 strains or lines available

References

• Original: J:283454 Wang L, et al., Quaking Deficiency Amplifies Inflammation in Experimental Endotoxemia via the Aryl Hydrocarbon Receptor/Signal Transducer and Activator of Transcription 1-NF-kappaB Pathway. Front Immunol. 2017;8:1754
• All: 2 reference(s)