Trim7^em1Jiew
Endonuclease-mediated Allele Detail

Summary

• Symbol: Trim7^em1Jiew
• Name: tripartite motif-containing 7; endonuclease-mediated mutation 1, Jie Wang
• MGI ID: MGI:6478305
• Synonyms: RNF90-deficient
• Gene: Trim7 Location: Chr11:48716965-48742019 bp, + strand Genetic Position: Chr11, 28.8 cM
• Alliance: Trim7^em1Jiew page

Mutation origin

• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Not Specified
• A knockout allele was created by targeting exon 3 using CRISPR/Cas9 technology. (J:292408)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Trim7 Mutation: 40 strains or lines available

References

• Original: J:292408 Yang B, et al., RNF90 negatively regulates cellular antiviral responses by targeting MITA for degradation. PLoS Pathog. 2020 Mar;16(3):e1008387
• All: 1 reference(s)