Bsg^tm1Itl
Targeted Allele Detail

Summary

• Symbol: Bsg^tm1Itl
• Name: basigin; targeted mutation 1, inGenious Targeting Laboratory
• MGI ID: MGI:6467013
• Synonyms: Bsg^flox
• Gene: Bsg Location: Chr10:79540325-79547803 bp, + strand Genetic Position: Chr10, 39.72 cM
• Alliance: Bsg^tm1Itl page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:288233
• Parent Cell Line: BAC-BA1 (ES Cell)
• Strain of Origin: (C57BL/6 x 129S/SvEv)F1

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of exon 1. A floxed and FRT-flanked neomycin resistance cassette was inserted downstream of exon 1. (J:288233)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Bsg Mutation: 15 strains or lines available

References

• Original: J:288233 Bisetto S, et al., New Insights into the Lactate Shuttle: Role of MCT4 in the Modulation of the Exercise Capacity. iScience. 2019 Dec 20;22:507-518
• All: 2 reference(s)