Pgc^{tm1(Hbegf)Koo}
Targeted Allele Detail

Summary

• Symbol: Pgc^{tm1(Hbegf)Koo}
• Name: progastricsin (pepsinogen C); targeted mutation 1, Bon-Kyoung Koo
• MGI ID: MGI:6456666
• Synonyms: Pgc-DTR
• Gene: Pgc Location: Chr17:48037767-48045403 bp, + strand Genetic Position: Chr17, 23.98 cM, cytoband C
• Alliance: Pgc^{tm1(Hbegf)Koo} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:287443
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Inserted expressed sequence, Reporter)
• Mutation: Insertion
• Pgc^{tm1(Hbegf)Koo} expresses 1 gene
  Knock-in expresses:
  

  Organism	Expressed Gene	Note
  Not Specified	Hbegf

• An IRES, Hbegf (DTR), T2a, and dsRed reporter gene were inserted after the coding sequence. (J:287443)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pgc Mutation: 20 strains or lines available

References

• Original: J:287443 Han S, et al., Defining the Identity and Dynamics of Adult Gastric Isthmus Stem Cells. Cell Stem Cell. 2019 Sep 5;25(3):342-356.e7
• All: 2 reference(s)