Mirc34^tm1.2Mrl
Targeted Allele Detail

Summary

• Symbol: Mirc34^tm1.2Mrl
• Name: microRNA cluster 34, including Mir449a through Mir449c; targeted mutation 1.2, Merck Research Laboratory
• MGI ID: MGI:6436279
• Gene: Mirc34 Location: Chr13:113172517-113174158 bp Genetic Position: Chr13, Syntenic

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:147112
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6NTac

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mirc34^tm1.2Mrl involves 1 genes/genome features (Cdc20b) View all
• Mutation details: The cluster containing Mir449a, Mir449b and Mir449c was flanked by loxP sites. The cluster Mir449 is embedded into intron 2 of the predicted mouse gene Cdc20b (ENSMUSG00000078926). Mir449c is located 206 bp downstream of the predicted exon 2 of the Cdc20b gene. The proximal LoxP site was inserted within these 206 bp. Recombination removed the selection cassette and microRNA cluster. (J:147112)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mirc34 Mutation: 1 strain or line available

References

• Original: J:147112 Taconic, Information obtained from Taconic website. MGI Direct Data Submission. 2006-2017
• All: 1 reference(s)