Lag3^tm1.1Mrl
Targeted Allele Detail

Summary

• Symbol: Lag3^tm1.1Mrl
• Name: lymphocyte-activation gene 3; targeted mutation 1.1, Merck Research Laboratory
• MGI ID: MGI:6434015
• Gene: Lag3 Location: Chr6:124881324-124888668 bp, - strand Genetic Position: Chr6, 59.17 cM
• Alliance: Lag3^tm1.1Mrl page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:147112
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6NTac

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: Exon 3 was flanked by loxP sites (size of loxP-flanked region is 0.8 kb). The positive selection marker (Puromycin resistance - PuroR) was flanked by FRT sites and inserted into intron 3. The conditional allele was generated after Flp-mediated recombination. (J:147112)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Lag3 Mutation: 37 strains or lines available

References

• Original: J:147112 Taconic, Information obtained from Taconic website. MGI Direct Data Submission. 2006-2017
• All: 2 reference(s)