Klb^tm1.2Mrl
Targeted Allele Detail

Summary

• Symbol: Klb^tm1.2Mrl
• Name: klotho beta; targeted mutation 1.2, Merck Research Laboratory
• MGI ID: MGI:6434014
• Gene: Klb Location: Chr5:65505657-65541350 bp, + strand Genetic Position: Chr5, 33.64 cM
• Alliance: Klb^tm1.2Mrl page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:147112
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6NTac

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exon 1 and 2.1 kb of sequence upstream of exon 1 (promoter region) were flanked by loxP sites (size of loxP-flanked region 3.3 kb). Recombination removed the seelection cassette. The constitutive allele was generated after cre-mediated recombination. (J:147112)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Klb Mutation: 60 strains or lines available

References

• Original: J:147112 Taconic, Information obtained from Taconic website. MGI Direct Data Submission. 2006-2017
• All: 1 reference(s)