Tg(tetO-Vegfc)1Ali
Transgene Detail

Summary

• Symbol: Tg(tetO-Vegfc)1Ali
• Name: transgene insertion 1, Kari Alitalo
• MGI ID: MGI:6423418
• Transgene: Tg(tetO-Vegfc)1Ali Location: unknown
• Alliance: Tg(tetO-Vegfc)1Ali page

Transgene origin

• Strain of Origin: FVB/N

Transgene description

• Transgene Type: Transgenic (Inducible, Inserted expressed sequence)
• Inducer: doxycycline/tetracycline
• Mutation: Insertion
• Tg(tetO-Vegfc)1Ali expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Vegfc (MGI:109124)

• Mutation details: The full-length mouse VEGF-C cDNA (GenBank NM_009506) was inserted downstream of a tet-responsive promoter. Two independent transgenic founder lines were obtained. The one with the stronger expression was chosen for further analysis. (J:141410)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:141410 Lohela M, et al., Transgenic induction of vascular endothelial growth factor-C is strongly angiogenic in mouse embryos but leads to persistent lymphatic hyperplasia in adult tissues. Am J Pathol. 2008 Dec;173(6):1891-901
• All: 9 reference(s)