Rnf112^tm1.1Ycl
Targeted Allele Detail

Summary

• Symbol: Rnf112^tm1.1Ycl
• Name: ring finger protein 112; targeted mutation 1.1, Yi-Chao Lee
• MGI ID: MGI:6393245
• Synonyms: Znf179^-
• Gene: Rnf112 Location: Chr11:61339268-61344957 bp, - strand Genetic Position: Chr11, 37.96 cM, cytoband B1.3
• Alliance: Rnf112^tm1.1Ycl page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:261055
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: LoxP sites were inserted to flank exons 4-7. An frt-flanked neomycin selection cassette was inserted 5' to the second loxP site in intron 7. Cre-mediated recombination removed exons 4-7 and the selection cassette. (J:261055)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rnf112 Mutation: 28 strains or lines available

References

• Original: J:261055 Tsou JH, et al., Important Roles of Ring Finger Protein 112 in Embryonic Vascular Development and Brain Functions. Mol Neurobiol. 2017 Apr;54(3):2286-2300
• All: 3 reference(s)